What is ED and PE?
As a Primary care provider, very commonly I get asked about erectile dysfunction and premature ejaculation. First thing I would like to clarify is that these issues are very common and almost 1 in 4 Indian men suffers from these in their lifetime. I would like to reassure you that you are not alone, and it is treatable with right approach and finding what causes these issues.
Why ED and PE are diffrent?
Many times, I heard that I took medication and it didn’t work or it has improved only one condition and other remains the same. This is very common scenario, not because medication is not working but you are only getting treatment for either ED or PE and not both. It is imperative that you need to get treated for both if you are experiencing ED and PE together
Why I need to treat ED and PE both?
Treatment of PE is totally different than treatment of ED. Both these problems need completely different medication. Medications that work for ED, for example Viagra, Sildenafil, Tadathrill, Tadalafil only improve weak erection and gives you stronger erection and has no role in delaying ejaculation. Vice versa medications which work for PE, for example Dapoxetine, Paroxetine only work for delaying ejaculation and have no role in getting proper erection. In short, mechanism of actions for both medicines are different and that is why treating only one will not improve other condition.
How ED and PE Medicine works?
Tadalafil or Sildenafil inhibits PDE5 which leads to increase in cyclic guanosine monophosphate (cGMP) levels. Increased cGMP will cause relaxation of smooth muscles and increase blood flow to blood vessels. This increase in blood flow to vessels in penis will lead to strong and hard erection. On the other side Dapoxetine is SSRI (Selective Serotonin Receptor Inhibitors), which increases level of synaptic serotonin. This increase caused stimulation of latency of PMRD reflex discharge and ultimately leads to prolonging time to ejaculation.
What is the best treatment for ED and PE combine?
If you are suffering from ED and PE, then you will need dual therapy of Tadalafil and Dapoxetine, as mentioned above both medications have different mechanisms of action. This dual treatment will address ED and PE both and you will be able to obtain stronger erection along with delaying your ejaculation. Tadathrill-D, is one of the dual therapies available on the market. It has Tadalafil 10 mg and Dapoxetine 30 mg together in 1 pill. Basically, it is 2 in 1 combination medicine and Seltyca’s Tadathrill-D will improve your erectile dysfunction (ED) and premature ejaculation (PE).
If you are facing ED ( Trouble getting erection, trouble maintaining erection, erection is not full, erection lasts only for some time) or you are having PE (Ejaculation time is fast, not able to perform,) then Seltyca’s Tadathrill-D will work best for you and will address both of your concern. Before you use any medication for your issues please consult doctor. Seltyca offers free doctor consultations.


